Ritonavir or lopinavir/ritonavir greatly enhance plasma concentrations of oxycodone in wholesome human volunteers as a consequence of inhibition of CYP3A4 and CYP2D6.[58] Rifampicin greatly reduces plasma concentrations of oxycodone because of solid induction of CYP3A4.We only use high-quality, credible resources to make certain content accuracy an

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